VIP 10mg

A research-grade peptide is only as good as the chain of documentation behind it, from the synthesis batch record to the third-party purity report that ships with the vial. Protide Health Lab provides VIP 10mg as a sterile-filtered lyophilised powder in sealed vials, each supported by a third-party HPLC-MS purity report and a certificate of analysis that is tied to the specific batch you receive.

VIP – vasoactive intestinal peptide – is a 28-amino-acid neuropeptide belonging to the glucagon/secretin superfamily, first isolated from porcine duodenum. It is distributed widely in the enteric and central nervous systems and acts on both VPAC receptors and, less potently, on PAC1 receptors. Lyophilisation extends shelf life and reduces the risk of hydrolysis during transit, which is why essentially all research peptides are distributed as a dry powder rather than as a pre-dissolved solution.

VIP 10mg Key Takeaways

• Compound class: endogenous 28-amino-acid neuropeptide (vasoactive intestinal peptide).
• Format: lyophilised research powder in a sealed glass vial.
• Vial sizes: 10mg.
• Purity: 99% (HPLC-MS verified, third-party tested).
• Price: $75 per vial.
• Fulfilment: domestic US shipping with a batch certificate of analysis.
• Status: for laboratory research use only; not for human or veterinary use.

Table of Contents

1. What Is VIP 10mg?
2. VIP 10mg Specifications
3. Research Overview
4. Reported Mechanism of Action
5. Purity, Testing and Certificates of Analysis
6. Handling, Storage and Reconstitution
7. Available Sizes and Pricing
8. How to Order VIP 10mg Online
9. Frequently Asked Questions
10. Related Research Peptides
11. References and Further Reading

What Is VIP 10mg?

You can obtain VIP 10mg from Protide Health Lab as a endogenous 28-amino-acid neuropeptide (vasoactive intestinal peptide) supplied in a sealed, batch-labelled vial. Each vial carries a certificate of analysis from an independent laboratory, and the material is screened for identity by mass spectrometry and for purity by high-performance liquid chromatography before it is released for sale.

Also known as: VIP, Vasoactive Intestinal Peptide, PHM27, vasoactive intestinal polypeptide.

Protide Health Lab publishes the analytical result rather than an efficacy claim. Before you design a study around VIP 10mg, review the certificate of analysis for the batch in question and confirm that the reported purity and the identity confirmation meet the acceptance criteria your protocol requires.

VIP 10mg Specifications

Property	Details
Product Contents	VIP 10mg Lyophilized Powder (99% purity) in 3mL vial.
Available Sizes	10mg
Peptide Type	Endogenous 28-amino-acid neuropeptide, glucagon/secretin superfamily
Purity	99% (HPLC-MS verified, third-party tested)
Molecular Formula	C 147 H 237 N 43 O 43 S
Molecular Weight	3325.86 g/mol
Sequence	His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
CAS Number	40077-57-4
CID	53314964
Synonyms	Vasoactive Intestinal Peptide, Vasoactive Intestinal Polypeptide
Appearance	White to off-white lyophilized powder
Storage	Store at ≤6°C, sealed, away from heat, light, and moisture.
Solubility	Soluble in water

These parameters describe the compound as it is released from storage. Where two different values appear for the same property – as with multi-component blends – the individual values apply to each constituent peptide, and the total vial content is given under available sizes.

Research Overview: Circadian rhythm and suprachiasmatic nucleus research

VIP 10mg appears in the scientific literature as a endogenous 28-amino-acid neuropeptide (vasoactive intestinal peptide) used in controlled laboratory investigation. The summaries below are drawn from published research and describe areas of study rather than any approved or intended use. When researchers search for buy vip online, the practical comparison points are the analytical method used, the batch number behind the certificate of analysis and the storage history of the vial, not the marketing copy.

Circadian rhythm and suprachiasmatic nucleus research

Studies grouped under Circadian rhythm and suprachiasmatic nucleus research generally treat VIP 10mg as a tool for examining cell-migration, proliferation and viability measurements. Because these endpoints are measured in controlled culture systems, results are usually reported against a vehicle control and a reference compound, which allows the contribution of the peptide itself to be separated from assay variability. Reproducibility in this line of work depends heavily on the consistency of the starting material across repeats.

VPAC receptor signalling

In VPAC receptor signalling, published work typically examines VIP 10mg from the perspective of signalling cross-talk between converging pathways. Reported findings in this area are most useful when the preparation is fully characterised, since an unquantified purity difference between batches can easily be mistaken for a biological effect. For a laboratory working in this field, the practical requirement is a peptide whose sequence identity and purity have been independently confirmed.

Vasodilation and smooth-muscle studies

Research interest in Vasodilation and smooth-muscle studies centres on how VIP 10mg behaves at the level of dose-dependent changes in cellular readouts. The literature in this area is not uniform: study designs differ in concentration range, exposure time and model system, so comparisons across papers should be made with attention to those parameters. This is one of the clearest reasons to insist on batch-level analytical documentation before designing an experiment.

Neuroinflammation and immune modulation

Within Neuroinflammation and immune modulation, investigators use VIP 10mg to probe receptor occupancy and downstream second-messenger activity. Endpoints here are typically quantitative – fluorescence, luminescence, chromatographic signal or imaging counts – which makes reproducible material quality a practical requirement rather than a formality. Reproducibility in this line of work depends heavily on the consistency of the starting material across repeats.

Gastrointestinal secretion models

Studies grouped under Gastrointestinal secretion models generally treat VIP 10mg as a tool for examining gene-expression shifts and protein-level endpoints. Because these endpoints are measured in controlled culture systems, results are usually reported against a vehicle control and a reference compound, which allows the contribution of the peptide itself to be separated from assay variability. For a laboratory working in this field, the practical requirement is a peptide whose sequence identity and purity have been independently confirmed.

cAMP/PKA pathway research

In cAMP/PKA pathway research, published work typically examines VIP 10mg from the perspective of enzyme kinetics and substrate handling. Reported findings in this area are most useful when the preparation is fully characterised, since an unquantified purity difference between batches can easily be mistaken for a biological effect. This is one of the clearest reasons to insist on batch-level analytical documentation before designing an experiment.

Reported Mechanism of Action

VIP signals predominantly through VPAC1 and VPAC2, which are Gs-coupled receptors that raise intracellular cAMP and activate protein kinase A. Peripherally this drives vasodilation, smooth-muscle relaxation and secretion; centrally VIP is studied as a regulator of circadian timing in the suprachiasmatic nucleus and as a modulator of neuroinflammation. Its role in the gut, lungs and immune tissue makes it a recurring tool in several research areas at once.

Because VIP 10mg is studied as a endogenous 28-amino-acid neuropeptide (vasoactive intestinal peptide), reported mechanisms are generally described at the level of receptor engagement, second-messenger generation and downstream gene or enzyme activity. Reproducing any of those observations depends on using material whose identity and purity have been independently confirmed.

Purity, Testing and Certificates of Analysis

Purity is the single most important variable in peptide research because impurities change the effective concentration of the active sequence and can introduce confounding biological activity. Batch documentation includes the HPLC chromatogram, the mass spectrometry identity confirmation and the reported purity percentage, all of which can be archived alongside your experimental records.

Independent analysis of this material reports 99% (HPLC-MS verified, third-party tested). The certificate of analysis records the method used, the chromatographic profile, the mass-spectrometric identity confirmation and the final purity value, and it is issued against the specific batch supplied. That distinction matters: an identity confirmation from mass spectrometry establishes that the principal peak corresponds to the expected molecular mass, while the chromatographic purity figure describes how much of the total peak area that principal peak represents. A third element of quality control, which is not visible on a purity number, is the water and salt content of the lyophilised powder – residual moisture and counter-ion content both change the effective concentration of the peptide when the vial is dissolved. If your protocol requires a specific acceptance threshold, verify it against the certificate of analysis for the batch you receive before beginning work, and file that document with your study records so the material can be traced later.

Handling, Storage and Reconstitution

Storing the lyophilised powder

Lyophilised material is best held at -20 degrees Celsius away from direct light; avoid repeated temperature cycling by keeping only the working aliquot at hand. Once reconstituted, the solution should be refrigerated at 2 to 8 degrees Celsius and used within a defined working window rather than stored indefinitely.

Reconstitution

Bacteriostatic water is the usual starting diluent, and a preserved 0.9% benzyl alcohol solution is a practical alternative when the same vial will be accessed more than once.

To calculate a working concentration, divide the mass of peptide in the vial by the volume of diluent added. For example, a 10mg vial dissolved in 2 mL of diluent gives approximately 5 mg/mL per mL. A convenient shorthand is that a 10mg vial dissolved in 2mL of diluent gives a 5mg/mL stock, while the same vial dissolved in 5mL gives 2mg/mL. Add the diluent slowly down the wall of the vial rather than directing the stream onto the powder, swirl gently instead of shaking, and never vortex a peptide solution: mechanical shear and foaming both encourage aggregation.

Laboratory handling practice

Prepare and handle VIP 10mg in an appropriate laboratory environment using clean technique. Work with gloves and eye protection, use dedicated glassware or single-use labware, and label every aliquot with the compound name, concentration, batch number and preparation date. When drawing from a multi-use vial, swab the stopper before and after use and keep the needle small to reduce coreing. Avoid repeated freeze-thaw cycles, because each thaw exposes the peptide to a fresh round of hydrolysis and aggregation; prepare single-use aliquots instead. Dispose of all peptide waste in accordance with your institution’s chemical-waste policy, and record the batch number in your laboratory notebook so that any analytical outlier can be traced back to a specific vial.

Available Sizes and Pricing

VIP 10mg is supplied as a single 10mg vial priced at $75.

Larger vial sizes are intended for laboratories that prepare working stocks in bulk or that run long series of repeat experiments, since a single larger vial reduces the number of separate preparations and therefore the batch-to-batch variability introduced by handling. Smaller vials are generally the better choice for dose-ranging studies where several concentrations are compared side by side.

How to Order VIP 10mg Online

Each order ships from domestic inventory with tracking information and the corresponding batch certificate of analysis, so documentation arrives with the material. Browse the full Peptides category listing, or compare other compounds in the same family: Oxytocin 10mg, ARA-290 16mg, DSIP.

Protide Health Lab supplies VIP 10mg from domestic inventory with same-day dispatch for orders received before the daily cut-off. Each order includes the batch-matched certificate of analysis, and shipment tracking is provided so that delivery can be confirmed. Keep the vial closed until it reaches the laboratory, then store it as described in the handling section above.

Frequently Asked Questions

What is VIP 10mg?

VIP – vasoactive intestinal peptide – is a 28-amino-acid neuropeptide belonging to the glucagon/secretin superfamily, first isolated from porcine duodenum It is supplied as a research reagent for in-vitro laboratory investigation, not as a therapeutic product..

What purity is VIP 10mg supplied at?

The material is released against independent analytical testing, with a reported purity of 99% (HPLC-MS verified, third-party tested). The certificate of analysis for your specific batch records the method used, the chromatographic profile and the mass-spectrometric identity confirmation, and it ships with the order.

What vial sizes of VIP 10mg are available?

VIP 10mg is supplied as a single 10mg vial.

How much does VIP 10mg cost?

VIP 10mg is priced at $75 per vial, and the batch certificate of analysis is included with the order.

What is VIP 10mg supplied as?

It is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. The dry format is the most stable way to ship and store a research peptide, and it keeps the material usable for longer than a pre-dissolved solution would.

How should VIP 10mg be stored?

Keep the sealed vial frozen at -20 degrees Celsius, protected from light, until you are ready to use it. After reconstitution, store the solution at 2 to 8 degrees Celsius and use single-use aliquots to avoid repeated freeze-thaw cycling, which accelerates hydrolysis and aggregation.

What diluent should be used to reconstitute VIP 10mg?

Bacteriostatic water is the usual choice; a preserved 0.9%% benzyl alcohol solution is a practical alternative when the same vial will be drawn from repeatedly. Add the diluent slowly down the vial wall, swirl gently and never vortex, because mechanical shear promotes aggregation. Divide the vial mass by the volume added to obtain your working concentration.

Is VIP 10mg intended for human use?

No. This product is a research chemical supplied for in-vitro laboratory investigation only. It is not intended for human or veterinary use, and it is not a treatment, diagnostic or supplement.

How can I confirm the certificate of analysis for my batch?

The certificate of analysis is matched to the batch number printed on the vial and is included with the shipment. Compare the reported purity and identity data against the acceptance criteria in your protocol and file the document with your study records so the material remains traceable.

Related Research Peptides

The following compounds are commonly ordered alongside VIP 10mg – either because they act on related pathways or because they belong to the same structural family.

• Oxytocin 10mg – cyclic nonapeptide neurohypophysial hormone with a disulfide bridge.
• ARA-290 16mg – synthetic 11-amino-acid non-haematopoietic erythropoietin-derived peptide.
• DSIP – synthetic nonapeptide (delta sleep-inducing peptide, 9 amino acids).
• LL-37 5mg – synthetic cathelicidin-derived peptide (37 amino acids).

The complete research catalogue is available on the https://protidehealthlab.store/shop/ page. If you are unsure which vial size fits your protocol, order the smaller size first, confirm that the material meets your acceptance criteria against the certificate of analysis, and scale up once the preparation has performed as expected. Every listing shows the analytical documentation for the batch, so the material can be evaluated on evidence before it is ordered.

References and Further Reading

The links below point to publicly indexed literature and reference resources relevant to this compound class. They are provided so that the mechanistic summaries above can be traced to their sources. Access to full text depends on the subscription arrangements of your institution.

• Peer-reviewed literature indexed in PubMed (PMID 3890590)
• Peer-reviewed literature indexed in PubMed (PMID 18641919)
• PubMed – biomedical literature database maintained by the National Library of Medicine
• National Institutes of Health – public research and health information resources

Research Use Only Disclaimer

This product is sold strictly as a chemical reference material for in-vitro laboratory research and is not a drug, supplement, cosmetic or food. It must not be administered to humans or animals, must not be used for diagnostic or therapeutic purposes, and must be handled only by qualified personnel in an appropriate laboratory setting. Statements describing areas of scientific interest are summaries of published research literature and do not constitute claims of efficacy, safety or intended use. By purchasing, the buyer confirms that they are a qualified researcher and that the material will be used lawfully within an institutional or laboratory research context.